A pleiotropic gene is a single gene that controls more than one trait. © 2008 Nature Education All rights reserved. View Terms of Use. During his study of

Evidence of gene–environment interactions between common breast cancer breast, prostate, and colorectal cancer reveals novel pleiotropic associations.

also plei·ot·ro·pism n. Biology The production of diverse effects, especially the production by a single gene of several distinct and seemingly unrelated Pleiotropic definition, responsible for or affecting more than one phenotypic characteristic: Scientists are trying to determine if the various effects of pleiotropic genes are sensitive in different ways to different environmental influences. pleiotropy [pli-ot´rŏ-pe] the production by a single gene of multiple phenotypic effects. The term is often used to refer to a single gene defect that is expressed as 2020-06-13 · Gene ID: 838122, updated on 13-Jun-2020. Summary. ABC transporter family involved in ABA transport and resistance to lead.

Pleiotropic gene

Ernst Caspari. Gene provides a unified query environment for genes defined by sequence and/or in NCBI's Map Viewer. codY GTP-sensing pleiotropic transcriptional regulator CodY [] Gene … 2007-06-01 2020-06-13 Pleiotropic effects stem from both normal and mutated genes, but those caused by mutations are often more noticeable and easier to study. Pleiotropy is actually more common than its opposite, since in a complex organism, a protein from a single gene is likely to be expressed in more than one tissue, and the cascade of problems caused by a mutation is likely to lead to numerous complications Intersex(ix), a gene involved in the sex-determining cascade of Drosophila melanogaster, works in concert with the female-specific product of doublesex (dsx) at the end of the hierarchy to implement the sex-specific differentiation of sexually dimorphic characters in female individuals.

Pleiotropic gene definition at Dictionary.com, a free online dictionary with pronunciation, synonyms and translation. Look it up now!

Department of Biology, Wesleyan University, Middletown, Conn. Search for more papers by this author. Ernst Caspari. Antagonistically pleiotropic genes are the explanation for fitness trade-offs.

For example, Marfan syndrome. Most genes have pleiotropy that indicates multiple phenotypic effects. In the case of humans, pleiotropic alleles are accountable

Shb is an SH2-domain adapter The effects of Shb are pleiotropic and context dependent. We have recently generated a Cassandra thinks that genes like these with complex histories and pleiotropic effects might be very common in living systems, much more than longstanding one Genome-wide association meta-analysis identifies pleiotropic risk loci for aerodigestive squamous cell cancers.

Answer Now and help others. Define pleiotropy. pleiotropy synonyms, pleiotropy pronunciation, pleiotropy translation, English dictionary definition of pleiotropy. also plei·ot·ro·pism n. Biology The production of diverse effects, especially the production by a single gene of several distinct and seemingly unrelated Pleiotropic definition, responsible for or affecting more than one phenotypic characteristic: Scientists are trying to determine if the various effects of pleiotropic genes are sensitive in different ways to different environmental influences. pleiotropy [pli-ot´rŏ-pe] the production by a single gene of multiple phenotypic effects.
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GeneRIFs: Gene References Into Functions. PRL1 is required for the accumulation of microRNAs (miRNAs) and small interfering RNAs (siRNAs). PRL1 positively influences the processing of miRNA primary transcripts (pri-miRNAs) and double-stranded RNAs (dsRNAs). Pleiotropy refers to the observation of a single gene influencing multiple phenotypic traits.
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Involved in pre-mRNA splicing as component of the spliceosome (PubMed:28502770, PubMed:28076346). Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing (PubMed:11101529, PubMed:11544257).

Functional Analyses for Pleiotropic Genes. We now undertake functional analyses for the 121 pleiotropic genes.